188 research outputs found

    Basic Criteria, Models, and Indicators of Intersectoral Collaboration in Health Promotion: A Scoping Review

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    Background: In this study, the basic criteria, models, and indicators of intersectoral collaboration in health promotion were investigated to facilitate the implementation of collaboration.&#x0D; Methods: This scoping review was conducted using datasets of Embase, Web of Science, Scopus, and PubMed, and search engines of Google, Google Scholar, and ProQuest.&#x0D; Results: 52 studies were included, and 32 codes in Micro, Meso, and Macro level, were obtained. Micro-level criteria had the highest frequency. Among the models used in the reviewed studies, social network analysis, Diagnosis of Sustainable Collaboration, Bergen, and logic models had the highest frequency. Among the indicators studied, the number of participants and the level of collaboration as well as its sustainability were the most frequent indicators.&#x0D; Conclusion: The findings identified the most important and widely used criteria, models, and indicators of intersectoral collaboration in health promotion which can be useful for decision-makers and planners in the domain of health promotion, in designing, implementing, and evaluating collaborative programs.</jats:p

    Land subsidence hazard in iran revealed by country-scale analysis of sentinel-1 insar

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    Many areas across Iran are subject to land subsidence, a sign of exceeding stress due to the over-extraction of groundwater during the past decades. This paper uses a huge dataset of Sentinel-1, acquired since 2014 in 66 image frames of 250×250km, to identify and monitor land subsidence across Iran. Using a two-step time series analysis, we first identify subsidence zones at a medium scale of 100m across the country. For the first time, our results provide a comprehensive nationwide map of subsidence in Iran and recognize its spatial distribution and magnitude. Then, in the second step of analysis, we quantify the deformation time series at the highest possible resolution to study its impact on civil infrastructure. The results spots the hazard posed by land subsidence to different infrastructure. Examples of road and railways affected by land subsidence hazard in Tehran and Mashhad, two of the most populated cities in Iran, are presented in this study

    Knowledge acquisition and technology transfer for the mass production of specific pathogen free (SPF) shrimp, towards independent on foreign production

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    In this study we collected the adult shrimp from farm in Bouhsher province based on the pedigree information and screening by PCR for 10 shrimp pathogen as well viral diseases and transported to the shrimp research station for first quarantine. Three different families were selected and crossed them and obtained the larval and produced F1generation. The F1 shrimp had reach an average weight (33±2g) and crossed together for produced F2 generation. The larval from F2 generation transferred to second quarantine and maintained in different tank. The postlarvae from F2 transferred to nuclear breeding center and cultured until the adult size. During F1 and F2 period we screened the shrimp for 10 pathogen and for prevention the inbreeding and transferring the growth and survival gen we used selection breeding with 12 primers by microsatellite technique during each generation. After 3 year we produced 8 thousand shrimp SPF and the shrimp are free of important viral disease as well WSSV

    Insight into blood pressure targets for universal coverage of hypertension services in Iran: the 2017 ACC/AHA versus JNC 8 hypertension guidelines

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    BACKGROUND: We compared the prevalence, awareness, treatment, and control of hypertension in Iran based on two hypertension guidelines; the 2017 ACC/AHA -with an aggressive blood pressure target of 130/80 mmHg- and the commonly used JNC8 guideline cut-off of 140/90 mmHg. We shed light on the implications of the 2017 ACC/AHA for population subgroups and high-risk individuals who were eligible for non-pharmacologic and pharmacologic therapies. METHODS: Data was obtained from the Iran national STEPS 2016 study. Participants included 27,738 adults aged ≥25 years as a representative sample of Iranians. Regression models of survey design were used to examine the determinants of prevalence, awareness, treatment, and control of hypertension. RESULTS: The prevalence of hypertension based on JNC8 was 29.9% (95% CI: 29.2-30.6), which soared to 53.7% (52.9-54.4) based on the 2017 ACC/AHA. The percentage of awareness, treatment, and control were 59.2% (58.0-60.3), 80.2% (78.9-81.4), and 39.1% (37.4-40.7) based on JNC8, which dropped to 37.1% (36.2-38.0), 71.3% (69.9-72.7), and 19.6% (18.3-21.0), respectively, by applying the 2017 ACC/AHA. Based on the new guideline, adults aged 25-34 years had the largest increase in prevalence (from 7.3 to 30.7%). They also had the lowest awareness and treatment rate, contrary to the highest control rate (36.5%) between age groups. Compared with JNC8, based on the 2017 ACC/AHA, 24, 15, 17, and 11% more individuals with dyslipidaemia, high triglycerides, diabetes, and cardiovascular disease events, respectively, fell into the hypertensive category. Yet, based on the 2017 ACC/AHA, 68.2% of individuals falling into the hypertensive category were eligible for receiving pharmacologic therapy (versus 95.7% in JNC8). LDL cholesterol< 130 mg/dL, sufficient physical activity (Metabolic Equivalents≥600/week), and Body Mass Index were found to change blood pressure by - 3.56(- 4.38, - 2.74), - 2.04(- 2.58, - 1.50), and 0.48(0.42, 0.53) mmHg, respectively. CONCLUSIONS: Switching from JNC8 to 2017 ACC/AHA sharply increased the prevalence and drastically decreased the awareness, treatment, and control in Iran. Based on the 2017 ACC/AHA, more young adults and those with chronic comorbidities fell into the hypertensive category; these individuals might benefit from earlier interventions such as lifestyle modifications. The low control rate among individuals receiving treatment warrants a critical review of hypertension services

    Exploring cloud-based platforms for rapid insar time series analysis

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    The idea of near real-time deformation analysis using Synthetic Aperture Radar (SAR) data as a response to natural and anthropogenic disasters has been an interesting topic in the last years. A major limiting factor for this purpose has been the non-availability of both spatially and temporally homogeneous SAR datasets. This has now been resolved thanks to the SAR data provided by the Sentinel-1A/B missions, freely available at a global scale via the Copernicus program of the European Space Agency (ESA). Efficient InSAR analysis in the era of Sentinel demands working with cloud-based platforms to tackle problems posed by large volumes of data. In this study, we explore a variety of existing cloud-based platforms for Multioral Interferometric SAR (MTI) analysis and discuss their opportunities and limitations

    Association of high risk human papillomavirus and breast cancer : a UK based study

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    Infection by human papillomaviruses (HPVs) has been implicated in the aetiology of a variety of cancers. Studies evaluating the presence of HPVs in breast cancer (BC) have generated considerable controversy. To date, most studies have focused on the presence of viral DNA in BC; however there are important gaps in evidencing the role of HPV persistence in the invasiveness of BC. While these studies have been conducted in several countries, none, on the presence and biological activity of high risk (HR) HPV in BC has been done in the UK. Hence, we aimed to investigate these gaps by screening a total of 110 fresh breast tissue specimens from UK patients for the presence of twelve HR-HPV types DNA using PCR and Sanger sequencing. Samples positive for HPV-DNA were screened for viral oncoprotein expression using western blot and dot blot. Data obtained showed the presence of HR-HPVs in 42% of breast tissues of which the viral activity was only confirmed in a number of invasive carcinomas (5/26). This finding, the first to report in the UK, suggests that the selective expression of viral oncoprotein in invasive cases may propose a role for HR-HPVs in the development of some types of BC

    Clinical Utility of a Unique Genome-Wide DNA Methylation Signature for KMT2A-Related Syndrome

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    Wiedemann\u2013Steiner syndrome (WDSTS) is a Mendelian syndromic intellectual disability (ID) condition associated with hypertrichosis cubiti, short stature, and characteristic facies caused by pathogenic variants in the KMT2A gene. Clinical features can be inconclusive in mild and unusual WDSTS presentations with variable ID (mild to severe), facies (typical or not) and other associated malformations (bone, cerebral, renal, cardiac and ophthalmological anomalies). Interpretation and classification of rare KMT2A variants can be challenging. A genome-wide DNA methylation episignature for KMT2A-related syndrome could allow functional classification of variants and provide insights into the pathophysiology of WDSTS. Therefore, we assessed genome-wide DNA methylation profiles in a cohort of 60 patients with clinical diagnosis for WDSTS or Kabuki and identified a unique highly sensitive and specific DNA methylation episignature as a molecular biomarker of WDSTS. WDSTS episignature enabled classification of variants of uncertain significance in the KMT2A gene as well as confirmation of diagnosis in patients with clinical presentation of WDSTS without known genetic variants. The changes in the methylation profile resulting from KMT2A mutations involve global reduction in methylation in various genes, including homeobox gene promoters. These findings provide novel insights into the molecular etiology of WDSTS and explain the broad phenotypic spectrum of the disease

    Impact assessment of master plan of "attain to technical knowledge of specific pathogen free shrimp production and cut off to dependence on foreign products" on Bushehr city environment: A case study, Shoghab research station

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    This study is a part of the national and technology master plan entitled "Attain to technical knowledge of specific pathogen free shrimp production and cut off to dependence on foreign products". The goals of this work were to assess the environmental effects of Specific Pathogen Free shrimp production complex on surrounded region in Persian Gulf (Shoghab) research station in Bushehr city. The environmental impacts were assessed in Persian Gulf (Shoghab) research station in Bushehr city by usage of simple checklist for impacts prediction, and scaling check list for assessment during Feb 2012 till Sep 2014. Flushing the effluents to the sea is the biggest concern of this project that can resulted in health impacts on aquatic and human communities that can be avoided by treatment. Low diversity in activities beside lack of environmental sensitive elements in the region leads us to use of scaling check list for impact assessment. Environmental grade of each activity can be achieved by stratification of them according to their intensity, significance and scale. We reached +320 and -198 for positive and negative points respectively that sounds a clear yes for execution choice

    Impact assessment of master plan of "attain to technical knowledge of specific pathogen free shrimp production and cut off to dependence on foreign products" on Bushehr city environment: A case study, Shoghab research station

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    This study is a part of the national and technology master plan entitled "Attain to technical knowledge of specific pathogen free shrimp production and cut off to dependence on foreign products". The goals of this work were to assess the environmental effects of Specific Pathogen Free shrimp production complex on surrounded region in Persian Gulf (Shoghab) research station in Bushehr city. The environmental impacts were assessed in Bandragah research station in Bushehr city by usage of comprehensive method for impacts prediction, and Pastakia Matrix for assessment during Feb 2012 till Sep 2014. Results showed 8 negative and 3 positive environmental factors that affect by operating phase including 48% very slightly negative and 44.5% slightly positive and 7.5% very slightly positive effects. Although there is no significant different between negative and positive effects but based on national strategy on getting the technology doing such a projects is highly recommended. By the usage of technical methods in effluents treatment control and reduction of bad impacts is achievable
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